Haemophagocytic reticulosis. A state of chimerism?

نویسندگان

  • G Blennow
  • B Berg
  • L Brandt
  • L Messeter
  • B Löw
  • N Söderström
چکیده

Haemophagocytic reticulosis is characterized by pancytopenia and an increased mass of reticuloendothelial cells in various organs containing engulfed blood cells (see Buist, Jones, and Cavens, 1971; Oehmichen, Narita, and Roloff, 1972; Nezelof and Eliachar, 1973). The pathogenesis is obscure. Autoimmunity, primary histiocytic proliferation, and a graft versus host reaction have been suggested. A case diagnosed during life is described where cytological and immunological studies as well as experiments with erythrophagocytosis in vitro suggest an immune reaction rather than a neoplastic histiocytic proliferation as the pathogenetic mechanism.

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عنوان ژورنال:
  • Archives of disease in childhood

دوره 49 12  شماره 

صفحات  -

تاریخ انتشار 1974